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Andrew McPherson Selected Research

4- chloro- 3- (5- methyl- 3- ((4- (2- pyrrolidin- 1- ylethoxy)phenyl)amino)- 1,2,4- benzotriazin- 7- yl)phenol

1/2009Development of novel benzotriazines for drug discovery.
3/2008Development of prodrug 4-chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl benzoate (TG100801): a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration.

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Andrew McPherson Research Topics

Disease

15Neoplasms (Cancer)
01/2022 - 02/2007
3Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 06/2017
3Triple Negative Breast Neoplasms
01/2021 - 04/2012
2Breast Neoplasms (Breast Cancer)
10/2019 - 01/2018
2Prostatic Neoplasms (Prostate Cancer)
05/2012 - 06/2011
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
09/2011 - 01/2011
2Macular Degeneration (Age-Related Maculopathy)
01/2009 - 03/2008
1Ascites
12/2021
1Pleural Effusion (Pleural Effusions)
12/2021
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
06/2017
1Hepatitis C
03/2013
1Chromothripsis
12/2012
1Neoplasm Metastasis (Metastasis)
07/2012
1Adenocarcinoma
05/2012
1Sarcoma (Soft Tissue Sarcoma)
01/2012
1Endometrial Stromal Sarcoma
01/2012
1Hodgkin Disease (Hodgkin's Disease)
03/2011
1Leukemia
01/2011
1Edema (Dropsy)
03/2008
1Choroidal Neovascularization
03/2008

Drug/Important Bio-Agent (IBA)

8RNA (Ribonucleic Acid)IBA
12/2019 - 01/2011
4DNA (Deoxyribonucleic Acid)IBA
12/2019 - 07/2012
4Biological ProductsIBA
12/2019 - 05/2012
2Hormones (Hormone)IBA
08/2014 - 05/2012
24- chloro- 3- (5- methyl- 3- ((4- (2- pyrrolidin- 1- ylethoxy)phenyl)amino)- 1,2,4- benzotriazin- 7- yl)phenolIBA
01/2009 - 03/2008
1Hematoxylin (Haematoxylon)IBA
01/2022
1Eosine Yellowish-(YS) (Eosin)IBA
01/2022
1Immune Checkpoint InhibitorsIBA
12/2021
1PhosphatidylserinesIBA
12/2021
1Cisplatin (Platino)FDA LinkGeneric
01/2021
1Peptide Hydrolases (Proteases)FDA Link
10/2019
1Collagenases (Collagenase)FDA Link
10/2019
1Small Cytoplasmic RNAIBA
10/2019
1NucleotidesIBA
07/2015
1Illicit Drugs (Recreational Drugs)IBA
03/2013
1Phenobarbital (Luminal)FDA Link
05/2012
1Progesterone Receptors (Progesterone Receptor)IBA
04/2012
114-3-3 Proteins (14-3-3 Protein)IBA
01/2012
1Oncogene Proteins (Oncogene Protein)IBA
01/2012
1Insulin-Like PeptidesIBA
09/2011
1phosphatidylinositol receptorsIBA
09/2011
1AndrogensIBA
06/2011
1MHC class II transactivator proteinIBA
03/2011
1LigandsIBA
03/2011
1MicroRNAs (MicroRNA)IBA
01/2011
1Tirapazamine (SR 4233)IBA
01/2009
1ProdrugsIBA
03/2008
1Benzoates (Benzoate)IBA
03/2008
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2008
1src-Family KinasesIBA
02/2007
1AminesIBA
02/2007

Therapy/Procedure

3Therapeutics
12/2021 - 05/2012
1Drug Therapy (Chemotherapy)
01/2021
1Precision Medicine
08/2014
1Ambulatory Care (Outpatient Care)
03/2013
1Transcutaneous Electric Nerve Stimulation (TENS)
12/2012
1Lasers (Laser)
03/2008